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1.
Int J Urol ; 2024 Apr 21.
Artigo em Inglês | MEDLINE | ID: mdl-38644653

RESUMO

AIM OF THE STUDY: The aim of our study is to evaluate the difference in stricture rate between matched groups of Bricker and Wallace techniques for ureteroileal anastomosis. PATIENTS AND METHODS: A retrospective analysis of patients undergoing urinary diversion (UD) with Bricker and Wallace ureteroileal anastomosis at two university hospitals. Two groups of Bricker and Wallace patients were matched in a 1:1 ratio based on the age, sex, body mass index (BMI), Charlson comorbidity index (CCI), preoperative hydronephrosis, prior radiation therapy or abdominal surgery, pathologic T and N stages and 30-days-Clavien grade complications≥III. A multivariable Cox regression analysis was conducted to identify predictors of ureteroenteric stricture (UES) in all patients. RESULTS: Overall, 740 patients met the inclusion criteria and 209 patients in each group were propensity matched. At a similar median follow-up of 25 months, UES was detected in 25 (12%) and 30 (14.4%) patients in Bricker and Wallace groups, respectively (p = 0.56). However, only one patient in the Bricker group developed a bilateral stricture compared to 15 patients in the Wallace group, resulting in a significantly higher number of affected renal units in the Wallace group: 45 (10.7%) versus only 26 (6.2%) in the Bricker group (p = 0.00). On multivariable extended Cox analysis, prior radiotherapy, presence of T4 pelvic malignancy and nodal positive disease were independent predictor of UES formation. CONCLUSION: The technique of ureteroileal anastomosis itself does not increase the rate of stricture; however, conversion of two renal units into one is associated with a higher incidence of bilateral upper tract involvement.

2.
Arab J Urol ; 22(1): 61-69, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38205387

RESUMO

Introduction: Ureteroenteric stricture (UES) is the leading cause of renal function deterioration after radical cystectomy (RC) and urinary diversion (UD). The aim of the present review is to summarize studies that discussed the risk factors associated with UES development. Identifying the responsible factors is of importance to help surgeons to modify their treatment or follow-up strategies to reduce this serious complication. Materials and Methods: A comprehensive search of the literature using the PubMed database was conducted. The target of the search was only studies that primarily aimed to identify risk factors of UES after RC and UD. References of searched papers were also checked for potential inclusion. Results: The search originally yielded a total of 1357 articles, of which only 15 met our inclusion criteria, comprising 13, 481 patients. All the studies were observational, and retrospective published between 2013 and 2022. The natural history of UES and the reported risk factors varied widely across the studies. In 13 studies, a significant association between some risk factors and UES development was demonstrated. High body mass index (BMI) was the most frequently reported stricture risk factor, followed by perioperative urinary tract infection (UTI), robotic-assisted radical cystectomy (RARC), occurrence of post-operative Clavian grade ≥ 3 complications and urinary leakage. Otherwise, many other risk factors were reported only once. Conclusion: The literature is still lacking well-designed prospective studies investigating predisposing factors of UES. The available data suggest that the high BMI, RARC and complicated postoperative course are the main risk factors for stricture formation.

3.
World J Urol ; 40(8): 2063-2070, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-35773357

RESUMO

BACKGROUND: Men with lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH), will have deterioration in the quality of life. Likewise, BPH can be complicated by damage to bladder function, bladder stones formation, hematuria, and impaired kidney function. The goal of treatment is to avoid all those effects caused by BPH. OBJECTIVE: To evaluate the efficacy of tadalafil alone, silodosin alone, and the combination of both in the treatment of LUTS associated with BPH. PATIENTS AND METHODS: Patients in our department with BPH who had LUTS were assigned randomly to three groups: A (101 patients) received tadalafil, 5 mg; B (102 patients) received silodosin, 8 mg; and group C (105 patients) received the combination of tadalafil, 5 mg, and silodosin, 8 mg. For all participants, we asses changes in the maximum urinary flow rate (Qmax), International Prostate Symptom Score (IPSS), International Index of Erectile Function (IIEF) score, Post-voiding urine (PVR) and all results were recorded and analyzed with the (SPSS) and Microsoft Excel 2010. RESULTS: Qmax, IPSS, PVR and IIEF score improved significantly more with the combination of tadalafil and silodosin than with either drug alone (p < 0.001). Three months after treatment, the mean Qmax values were 14.4 ml/sec in group A, 15.2 ml/sec in group B, and 15.8 ml/sec in group C; and the mean IPSSs were 17.6 in group A, 16.7 in group B, and 15.6 in group C (p < 0.001). CONCLUSION: Tadalafil and silodosin are effective treatment options in men with BPH who have LUTS, but the combination of both is more effective and feasible in treating LUTS of BPH.


Assuntos
Disfunção Erétil , Sintomas do Trato Urinário Inferior , Hiperplasia Prostática , Disfunção Erétil/tratamento farmacológico , Humanos , Indóis , Sintomas do Trato Urinário Inferior/tratamento farmacológico , Sintomas do Trato Urinário Inferior/etiologia , Masculino , Inibidores da Fosfodiesterase 5/uso terapêutico , Estudos Prospectivos , Hiperplasia Prostática/complicações , Hiperplasia Prostática/tratamento farmacológico , Qualidade de Vida , Tadalafila/uso terapêutico , Resultado do Tratamento
4.
World J Urol ; 39(12): 4477-4482, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34076752

RESUMO

OBJECTIVE: To assess the effect and outcome of percutaneous nephrolithotomy (PNL) versus extracorporeal shock wave lithotripsy (SWL) in patients with renal insufficiency. PATIENTS AND METHODS: A prospective randomized clinical study of 104 renal insufficiency patients with renal stones (serum creatinine 2-4 mg/dl and eGFR < 60 ml/min/1.73 m2 more than 3 months) randomized into two groups: Group A underwent PNL; Group B underwent shock wave lithotripsy (SWL). Treatment effects and outcomes compared between the two groups. RESULTS: Between Group A of 50 patients and Group B of 54 cases, demographic data showed no statistically significant differences. The stone-free rate was 84% in Group A versus 26.6% in Group B after the first SWL session. After completion of all SWL sessions, the rate was 88.9% for Group B. Comparing pre and postoperative results of Group A, there is significant improvement of serum creatinine concentrations by 9.1% (p = 0.001), significant improvement of creatinine clearance (p = 0.000) and eGFR (p = 0.003). Although regarding Group B preoperatively and 3 months after SWL there is significant improvement by 8.7% (p = 0.0001), which is less than that of Group A, there is also, improvement of eGFR by 6.7% (p = 0.001), which is less than the eGFR improvement in Group A (12.3%). But there is no statistically significant difference is noted for creatinine clearance in Group B (p = 0.09). CONCLUSION: The outcomes for PNL and SWL in patients with renal insufficiency and renal stones are encouraging as minimally invasive procedures with no negative effects on kidney function.


Assuntos
Cálculos Renais/complicações , Cálculos Renais/terapia , Litotripsia , Nefrolitotomia Percutânea , Insuficiência Renal/etiologia , Insuficiência Renal/terapia , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Resultado do Tratamento
5.
World J Urol ; 37(5): 937-941, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-30167831

RESUMO

OBJECTIVE: To assess the effect of artificial hydronephrosis on the result of shock wave lithotripsy (SWL) in preschool children. MATERIALS AND METHODS: A prospective randomized trial was performed between January 2013 and January 2017 with 300 pediatric patients, having kidney stones with a size of 1-2 cm and a density of 750-1100 HU. The patients were randomized into two groups: group A, in which a ureteric catheter was fixed and artificial hydronephrosis was performed by fluid irrigation prior to SWL, and group B which did not undergo hydronephrosis. SWL outcomes were compared between two groups. RESULTS: In total, 153 cases were assigned to group A, and 147 cases were assigned to group B. Regarding demographic data, there was no statistically significant difference between the two groups. There were also no statistically significant differences in the number of shocks and energy power needed for each group. The results of SWL after the first session favored group A with a stone-free rate (SFR) of 90.8% vs. 75.5% for group B. The SFR after SWL was significantly in favor of group A (94.1%) vs. (86.4%) for group B. CONCLUSION: The use of an artificial hydronephrosis technique to make interface around the stone improves stone-free rate and decreases the need for retreatment after SWL.


Assuntos
Cálculos Renais/terapia , Litotripsia/métodos , Irrigação Terapêutica/métodos , Criança , Pré-Escolar , Feminino , Humanos , Hidronefrose , Lactente , Masculino , Retratamento , Resultado do Tratamento , Cateterismo Urinário
6.
Int. braz. j. urol ; 44(1): 163-171, Jan.-Feb. 2018. tab, graf
Artigo em Inglês | LILACS | ID: biblio-892955

RESUMO

ABSTRACT Purpose To evaluate the surgical outcome and predictors of failure of substitution urethroplasty using either dorsal onlay buccal mucosal (BM) graft or ventral onlay penile skin flap (PS) for anterior urethral stricture ≥ 8cm. Patients and methods Between March 2010 and January 2016, 50 patients with anterior urethral stricture ≥ 8 cm were treated at our hospital. The surgical outcome and success rate were assessed. The predictors of failure were analyzed using multivariate analysis. Failure was considered when subsequent urethrotomy or urethroplasty were needed. Results Dorsal onlay BM graft was carried out in 24 patients, while PS urethroplasty in 26 patients. There was no significant difference between both groups regarding patients demographics, stricture characteristics or follow-up period. One case in the BM group was lost during follow-up. Stricture recurrence was detected in 7 (30.4%) patients out of BM group while in 6 (23.1%) patients out of PS group (p value= 0.5). No significant differences between both groups regarding overall early and late complications were observed. Occurrence of early complications and the stricture length were the only predictors of failure in univariate analysis, while in multivariate analysis the occurrence of early complications was only significant. Conclusion On short-term follow-up, both dorsal onlay BM graft and ventral onlay PS flap urethroplasty have similar success rates. However, BM graft has a potential advantage to reduce operative time and is also technically easier. The surgeon should avoid early local complications as they represent a higher risk for failure.


Assuntos
Humanos , Masculino , Adulto , Pênis , Procedimentos Cirúrgicos Urológicos Masculinos , Retalhos Cirúrgicos/transplante , Estreitamento Uretral/cirurgia , Transplante de Pele/métodos , Mucosa Bucal/transplante , Estreitamento Uretral/patologia , Estudos Retrospectivos , Seguimentos , Resultado do Tratamento , Pessoa de Meia-Idade
7.
Int Braz J Urol ; 44(1): 163-171, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29211404

RESUMO

PURPOSE: To evaluate the surgical outcome and predictors of failure of substitution urethroplasty using either dorsal onlay buccal mucosal (BM) graft or ventral onlay penile skin flap (PS) for anterior urethral stricture ≥ 8cm. PATIENTS AND METHODS: Between March 2010 and January 2016, 50 patients with anterior urethral stricture ≥ 8 cm were treated at our hospital. The surgical outcome and success rate were assessed. The predictors of failure were analyzed using multivariate analysis. Failure was considered when subsequent urethrotomy or urethroplasty were needed. RESULTS: Dorsal onlay BM graft was carried out in 24 patients, while PS urethroplasty in 26 patients. There was no significant difference between both groups regarding patients demographics, stricture characteristics or follow-up period. One case in the BM group was lost during follow- up. Stricture recurrence was detected in 7 (30.4%) patients out of BM group while in 6 (23.1%) patients out of PS group (p value= 0.5). No significant differences between both groups regarding overall early and late complications were observed. Occurrence of early complications and the stricture length were the only predictors of failure in univariate analysis, while in multivariate analysis the occurrence of early complications was only significant. CONCLUSION: On short-term follow-up, both dorsal onlay BM graft and ventral onlay PS flap urethroplasty have similar success rates. However, BM graft has a potential advantage to reduce operative time and is also technically easier. The surgeon should avoid early local complications as they represent a higher risk for failure.


Assuntos
Mucosa Bucal/transplante , Pênis , Transplante de Pele/métodos , Retalhos Cirúrgicos/transplante , Estreitamento Uretral/cirurgia , Procedimentos Cirúrgicos Urológicos Masculinos , Adulto , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Resultado do Tratamento , Estreitamento Uretral/patologia
9.
Urology ; 82(2): 448-50, 2013 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-23688377

RESUMO

OBJECTIVE: To evaluate the safety and efficacy of percutaneous suprapubic stone extraction (PSPSE) for pediatric posterior urethral stones. METHODS: Between July 2007 and June 2010, 54 boys presenting with acute urinary retention due to posterior urethral stones underwent PSPSE. Patients were a mean age of 66.4 months (range, 8-180 months). The stone size was 0.7-1.9 cm. Patients were placed under general anesthesia, and a 7F urethroscope was used to pushback the stone to the bladder. A 3-mm suprapubic puncture with a scalpel was performed, followed by insertion of a straight narrow hemostat through the puncture aided with cystoscopic guidance. The stone was grasped with the hemostat in its narrowest diameter and was extracted percutaneously or crushed if friable. The suprapubic puncture was closed with a single 4-0 Vicryl (Ethicon) suture. RESULTS: Intact stone retrieval was achieved in 45 patients, and the stone was crushed into minute fragments in 9 patients. Intraperitoneal extravasation developed in 1 patient that required open surgical intervention. Mean operative time was 22 minutes. Patients were monitored for up to 17 months, with complete resolution of symptoms and stone clearance. CONCLUSION: PSPSE provides a minimally invasive approach for the extraction of urethral and bladder stones in the pediatric population. The use of a straight hemostat for suprapubic stone extraction or crushing is a good alternative to suprapubic tract dilation, with minimal morbidity.


Assuntos
Doenças Uretrais/cirurgia , Bexiga Urinária/cirurgia , Cálculos Urinários/cirurgia , Adolescente , Criança , Pré-Escolar , Cistoscopia , Humanos , Lactente , Tempo de Internação , Masculino , Procedimentos Cirúrgicos Minimamente Invasivos/efeitos adversos , Duração da Cirurgia , Procedimentos Cirúrgicos Urológicos/efeitos adversos
10.
Int Urol Nephrol ; 44(3): 661-6, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-22350835

RESUMO

PURPOSE: The continued evolution of stone treatment modalities, such as endourologic procedures, open surgery and shock wave lithotripsy, makes the assessment of continuous outcomes are essential. Pediatric urolithiasis are an important health problem allover the world, especially in Middle East region. We evaluate the safety, efficacy and factors affecting success rate and clearance of stones in children treated with shock wave lithotripsy. PATIENT AND METHODS: Between 2005 and 2010, a total of 500 children with stones in the upper urinary tract at different locations were treated by Extracorporeal shock wave lithotripsy (ESWL) in our department, Sohag University, Egypt. We have used the Siemn's Lithostar Modularis machine, Germany. A total of 371 boys and 129 girls with the average age of 8.63 ± 5 years, and a range from 9 months to 17 years were included in this study. Diagnosis of their urinary calculi was established either by the use of abdominal ultrasound, plain X-ray, intravenous urography, or CT scan. The stones were located in the kidney in 450 (90%) patients; 298 (66%) pelvic, 26 (5.7%) upper calices, 57 (12.6%) mid calices, and lower calices in 69 (15.3%) patients. The average of their stone sizes was 12.5 ± 7.2 mm. The other 50 children their stone were located in the proximal ureteral stones in 35 patients (70%); middle third in 5 (10%) patients and in the distal ureter in 10 (20%) patients. The average ureteral stone size was 7.5 ± 3.2 mm. All children were treated under general anesthesia with adequate lung and testes shielding using air foam. We treated the distal ureteral stones of young children in the supine position through greater sciatic foramen and lesser sciatic foramen as the path of shockwave instead of prone position, which is not a comfortable or natural position and could adversely affect cardiopulmonary function especially under general anesthesia. Localization was mainly done by ultrasound, and X-ray was only used to localize ureteral calculi. For follow-up, we have used abdominal ultrasound, plain X-ray, and CT scan if needed to confirm stone disintegration and clearance. RESULTS: The overall success rate for renal and ureteral calculi was 83.4 and 58.46%, respectively. The re-treatment rate was 4% in renal group and 28% for the ureteral group. No serious complications were recorded in our patients. Minor complications occurred in 15% of our patients; renal colic was reported in 10% of our treated patients, and repeated vomiting was reported in 5% that respond to antiemetics. In the renal group; children with history of pervious urologic surgical procedures had low success rate of stone clearance after ESWL. In the ureteral group stone burden, stone location, had a significant impact on stone clearance outcome. CONCLUSION: This study showed that SWL in pediatric age group for both renal and ureteral stone is cost effective, safe with an acceptable re-treatment rate; however children with large stone burden or previous urologic surgery have low success rate.


Assuntos
Cálculos Renais/terapia , Litotripsia , Cálculos Ureterais/terapia , Adolescente , Anestesia Geral , Criança , Pré-Escolar , Egito , Feminino , Humanos , Lactente , Cálculos Renais/diagnóstico por imagem , Litotripsia/efeitos adversos , Masculino , Radiografia , Cólica Renal/etiologia , Retratamento , Estudos Retrospectivos , Resultado do Tratamento , Ultrassonografia , Cálculos Ureterais/diagnóstico por imagem
11.
Arab J Urol ; 10(2): 182-5, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-26558023

RESUMO

OBJECTIVES: To evaluate the safety and clinical efficacy of the transobturator vaginal tape 'inside-out' (TVT-O) procedure for managing new-onset stress urinary incontinence (SUI) after radical cystectomy (RC) and orthotopic W-neobladder construction in women. PATIENTS AND METHODS: Between January 2004 and June 2010, 57 women were treated with RC and orthotopic ileal neobladder reconstruction. Six of these patients (median age 44 years, range 39-62; grade 2 muscle-invasive squamous cell carcinoma in four and transitional cell carcinoma in two) developed de novo SUI that was moderate in four and severe in two. The median (range) duration of SUI was 11 (9-18) months. All six patients underwent TVT-O for control of their SUI. RESULTS: Four patients were completely dry day and night (three of them can initiate voiding and one cannot, and uses intermittent catheterization). One patient improved, as assessed by using fewer pads (from 5-7 pads to 1 pad/day and night). She can initiate voiding but has minimal leakage only on moderate exertion. One patient who had severe SUI showed no improvement. Patients were followed for a mean (range) of 18 (17-32) months, with no deterioration in the continence status. CONCLUSION: These encouraging results confirm the safety and clinical efficacy of TVT-O for managing new-onset SUI after RC and ileal neobladder construction, although a larger survey and a longer follow-up are needed.

12.
Arab J Urol ; 9(4): 267-71, 2011 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26579310

RESUMO

OBJECTIVE: To evaluate and update the clinical and surgical outcome of orthotopic diversion in an eligible cohort of women with bladder carcinoma. PATIENTS AND METHODS: From 1999 to 2010, 78 women (mean age 42.4 years) had a radical cystectomy (RC) with orthotopic diversion using ileal neobladder reconstruction to treat invasive bladder carcinoma. The mean (SD) follow-up was 62 (25) months. RESULTS: The histopathological pattern was squamous cell carcinoma in 52 (67%) patients, transitional cell carcinoma in 17 (22%), mixed in four (5%) and undifferentiated carcinoma in five (6%). Three patients were completely incontinent day and night. Stress urinary incontinence after this surgery was reported in 11 (14%) patients, with daytime continence reported in 64 (82%); 59 (76%) patients were completely continent day and night. Chronic retention developed in nine (12%) patients. There was pouch prolapse through the vaginal stump in five (6%) patients, and a pouch-vaginal fistula in seven (9%). Sexual dysfunction was reported in 45 (69%) patients of 65 sexually active women. Stones formed in the pouch in five (6%) patients, while there were renal stones in four renal units. Oncological recurrence was reported in 15 (19%) patients, which was local in 11 (14%) and distant in four (5%). CONCLUSION: The long-term results showed that orthotopic neobladder construction after RC in women provides oncological safety and is functionally effective with proper surgical technique. Removal of the gynaecological organs during RC in women might be unnecessary for low-grade, low-stage tumour.

13.
Urology ; 76(4): 971-5; discussion 975, 2010 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-20932415

RESUMO

OBJECTIVES: To evaluate the use of buccal mucosa tubal graft for reconstruction of extensive ureteral stricture. MATERIAL AND METHODS: Between April 2006 and July 2008, 5 patients (mean age, 51.2 years) underwent reconstructive ureteral surgery for ureteral obstruction using buccal mucosa graft. The indication of surgery was extensive ureteral stricture of a 4.4-cm average length (range, 3.5-5.0). The site of stricture was in the proximal and the middle ureter in 3 and 2 patients, respectively. The causes of stricture were postinflammatory (3 cases) and iatrogenic after ureteroscopic procedures for impacted stones (2 cases). RESULTS: All 5 patients underwent successful ureteral defect replacement using buccal mucosal tube. The intraoperative course was uneventful without any major complications. Mean operative time was 106 minutes (range, 85-130). With a mean follow-up of 24 months (range, 14-39), the operated kidneys showed no obstruction. CONCLUSIONS: Oral buccal mucosal tubal graft for reconstruction of extensive ureteral stricture is a good available option. Although the results of this initial experience are encouraging, a bigger series and longer follow-up is recommended to evaluate our procedure.


Assuntos
Mucosa Bucal/transplante , Ureter , Obstrução Ureteral/cirurgia , Idoso , Constrição Patológica , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias/etiologia , Complicações Pós-Operatórias/cirurgia , Procedimentos de Cirurgia Plástica/métodos , Estudos Retrospectivos , Transplante Heterotópico , Resultado do Tratamento , Ureter/patologia , Ureter/cirurgia , Cálculos Ureterais/cirurgia , Obstrução Ureteral/etiologia , Ureteroscopia
15.
J Pediatr Urol ; 6(4): 403-7, 2010 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-19857999

RESUMO

OBJECTIVE: To evaluate the neourethra covering created by a vascularized overlapping double-layered dorsal dartos flap for preventing urethrocutaneous fistula in the Snodgrass hypospadias repair (tubularized incised plate). PATIENTS AND METHODS: Between March 2003 and January 2008, 156 boys (mean age, 4.5 years) were enrolled for hypospadias repair. Preoperative position of the urethral meatus was subcoronal in 37, at the distal shaft in 61 and mid-shaft in 58 boys. All patients underwent the Snodgrass hypospadias repair. The neourethra was then covered with an overlapping double-layered dorsal dartos flap before glans and skin closure. RESULTS: All 156 patients underwent successful reconstruction. With a mean follow up of 23 months (range 6-42), all boys had a satisfactory subjective cosmetic and functional result with a vertically oriented, slit-like meatus at the tip of the glans. No urethrocutaneous fistula or urethral stenosis occurred. CONCLUSION: As the neouretha covering is an integral part of the Snodgrass hypospadias repair, a dorsal well vascularized double-layered dartos flap is a good choice for preventing urethrocutaneous fistula formation.


Assuntos
Hipospadia/cirurgia , Retalhos Cirúrgicos , Adolescente , Criança , Pré-Escolar , Humanos , Lactente , Masculino , Procedimentos Cirúrgicos Urológicos Masculinos/métodos
16.
Int J Urol ; 15(7): 593-7, 2008 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-18479354

RESUMO

OBJECTIVES: We retrospectively evaluated our experience with a relatively uncommon procedure, the laparoscopic ureterolithotomy, for the treatment of ureteral stones. METHODS: Between April 2002 and October 2006, a total of 74 patients (56 males, 18 females) with upper (54 cases), middle (18 cases) and lower (two cases) ureteral stones underwent laparoscopic ureterolithomy. The mean age was 39.4 years (range, 19-74). The stones were in the right side in 44 cases (59.5%) and in the left side in 30 (40.5%) cases. The mean stone size was 1.8 cm (range 1.5-2.8). The procedure was retroperitoneal in 66 cases (89.2%) and transperitoneal in eight (10.8%) cases. Laparoscopic guided flexible ureterorenoscopic extraction of kidney stone was carried out in one case as an adjuvant procedure. The ureter was stented and not sutured in 64 cases (86.5%). RESULTS: The procedure was successfully completed in 94.6% of cases and an open conversion was carried out in four (5.4%) patients. The mean operative time was 58.7 min, and the mean blood loss was 90.6 mL. No major complications were encountered. Prolonged urinary leakage occurred in one patient. The mean hospital stay was 6.4 days. One patient developed ureteral stricture during follow up and was treated by endoscopic dilatation and stenting. CONCLUSION: In our experience laparoscopic ureterolithotomy represents a safe and effective treatment option for ureteral stones either as primary for large impacted stones or as a salvage procedure after failed shock wave lithotripsy or ureteroscopy. This procedure fulfills the advantages of minimal blood loss and analgesia requirements, good cosmetic appearance, short hospital stay and convalescence period.


Assuntos
Laparoscopia , Cálculos Ureterais/cirurgia , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Procedimentos Cirúrgicos Urológicos/métodos , Adulto Jovem
17.
J Med Invest ; 55(1-2): 147-50, 2008 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-18319558

RESUMO

From May, 1999 to August, 2006, we performed laparoscopic diagnosis and treatment for 103 cases of impalpable testes. Among those we found 5 cases of male pseudohermaphroditism of different etiologies. Three males presented by impalpable testes with ambiguous genitalia and 2 females presented by primary amenorrhea. All of them have 46-XY normal male chromosomal pattern. In the first 3 cases, the etiology was complete gonadal dysgenesis, and 2 cases with persistent Mullerian syndrome. Timed gonadectomy for the first case and laparoscopic orchiopexy for the other 2 cases were performed. For the other 2 female cases, the etiology was complete androgen insensitivity syndrome and laparoscopic bilateral orchiectomy was performed for both of them. All the procedures were done without complications with satisfactory results.


Assuntos
Transtornos do Desenvolvimento Sexual/cirurgia , Adulto , Síndrome de Resistência a Andrógenos/complicações , Criança , Pré-Escolar , Constrição Patológica/complicações , Transtornos do Desenvolvimento Sexual/diagnóstico , Transtornos do Desenvolvimento Sexual/etiologia , Transtornos do Desenvolvimento Sexual/genética , Feminino , Disgenesia Gonadal/complicações , Gônadas/cirurgia , Humanos , Laparoscopia , Masculino , Ductos Paramesonéfricos/patologia , Resultado do Tratamento
18.
Scand J Urol Nephrol ; 42(1): 59-62, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-17853008

RESUMO

OBJECTIVE: To evaluate the potential role of tamsulosin in the medical treatment of distal ureteral stones. MATERIAL AND METHODS: Ninety patients with symptomatic distal ureteral calculi were enrolled. They were randomly divided into two groups: Group A (n=45) received diclofenac 100 mg on demand for 4 weeks plus levofloxacin 250 mg daily for the first week and were well hydrated; and Group B (n=45) received the same therapy plus tamsulosin 0.4 mg/daily for 4 weeks. Abdominal ultrasound scans and KUB X-rays were performed weekly. Stone expulsion rates, time to expulsion, pain episodes and analgesic usage were determined. Intervention by means of shock-wave lithotripsy (SWL) or ureteroscopy was evaluated. RESULTS: The stone expulsion rate was 51.1% for Group A, compared to 88.9% for Group B (p=0.001). The average time to expulsion was 12.53+/-2.12 days for Group A and 7.32+/-0.78 days for Group B (p=0.04). The number of pain episodes was significantly lower in Group B and mean use of analgesics was lower for Group B (0.14+/-0.5 vials) than Group A (2.78+/-2.7 vials). Twenty-two patients in Group A failed to pass their stones after 4 weeks but only five in Group B. Of the patients who were not stone-free, 19 were treated with SWL and eight underwent ureteroscopy. CONCLUSION: Our study reveals the efficacy of tamsulosin for the treatment of distal ureteral stones. Tamsulosin should be added to the standard medical approach for treating these stones.


Assuntos
Antagonistas Adrenérgicos alfa/uso terapêutico , Sulfonamidas/uso terapêutico , Cálculos Ureterais/tratamento farmacológico , Adolescente , Adulto , Anti-Inflamatórios não Esteroides/uso terapêutico , Diclofenaco/uso terapêutico , Quimioterapia Combinada , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Tansulosina , Fatores de Tempo , Resultado do Tratamento , Cálculos Ureterais/diagnóstico
19.
J Endourol ; 21(5): 525-9, 2007 May.
Artigo em Inglês | MEDLINE | ID: mdl-17523907

RESUMO

PURPOSE: To evaluate transperitoneal ureterolithotomy by laparoscopy (TPUL) for the management of recurrent lower-ureteral stones previously treated with open surgery. PATIENTS AND METHODS: Between January 2003 and June 2006, 11 patients (mean age 35.2 years) with recurrent large (mean size 2.8 cm) lower-ureteral calculi and normal renal function underwent TPUL. Seven stones were on the left side, and the remaining four were on the right side. These stones were recurrent after previous open ureterolithotomy. Earlier attempts with ureteroscopy (for three patients) had failed. RESULTS: The TPUL was successful in all cases. The mean operating time was 85.2 minutes. Two patients required no narcotic analgesics, while the other patients received a mean of 2.3 10-mg doses of morphine sulfate for postoperative pain relief. The mean hospital stay was 3.8 days. The mean convalescence period was 13.7 days. There were no major intraoperative or postoperative complications. Prolonged urine leakage for 7 and 9 days occurred in two patients, which was managed conservatively. All patients were asymptomatic, stone free, and without obstruction or stricture formation on follow-up that included abdominal ultrasonography and plain films after 6 weeks and intravenous urography after 6 months. There was no deterioration of renal function. CONCLUSIONS: Laparoscopic transperitoneal ureterolithotomy is a feasible technique for the management of recurrent lower-ureteral stones after previous open ureterolithotomy that are not amenable to ureteroscopy or SWL. It is a minimally invasive, less-morbid alternative to open transperitoneal ureterolithotomy.


Assuntos
Laparoscopia/métodos , Ureter/cirurgia , Cálculos Ureterais/cirurgia , Procedimentos Cirúrgicos Urológicos/métodos , Adolescente , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Minimamente Invasivos/métodos , Estudos Prospectivos , Recidiva , Resultado do Tratamento
20.
Int J Urol ; 13(11): 1421-4, 2006 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-17083396

RESUMO

AIMS: Treatment of patients with abdominal non-palpable testis (NPT) is still controversial among pediatric urologists. This is a prospective randomized comparative study between open and laparoscopic orchiopexy for management of abdominal testis. The aim of this study was to evaluate the success rate and morbidity of both approaches. METHODS: Eighty-two patients with a mean age of 5.3 years were evaluated by laparoscopy for 87 NPT. Patients with viable abdominal testes were randomly treated with either open or laparoscopic orchiopexy procedures. RESULTS: On laparoscopy, 75 viable abdominal testes were found. According to location: 41 (47.1%) testes were high abdominal, 27 (31%) testes were low abdominal and 7 (8%) testes were peeping from the internal ring. Laparoscopic first stage Fowler-Stephens orchiopexy was done initially for those with high abdominal testes. For further management, all patients were divided randomly into open (36 cases) and laparoscopic (39 cases) groups where primary (with spermatic vessel preservation) or second stage Fowler-Stephens orchiopexy was done. Statistical analysis was done using Student's t-test. Laparoscopic procedures showed significant less morbidity than the open counterparts. Follow up ranged from 9 to 31 months and included evaluation of testicular site and size. All testes were located satisfactorily inside the scrotum. Five cases of testicular atrophy were encountered (three and two testes with open and laparoscopic second stage Fowler-Stephens orchiopexy respectively) after 1 year follow up. CONCLUSION: Results of open versus laparoscopic orchiopexy procedures (primary or staged) are fairly comparable. However, laparoscopy provides significantly less morbidity.


Assuntos
Criptorquidismo/cirurgia , Laparoscopia/métodos , Orquiectomia/métodos , Testículo/cirurgia , Adolescente , Criança , Pré-Escolar , Criptorquidismo/patologia , Humanos , Lactente , Masculino , Estudos Prospectivos , Testículo/anormalidades , Resultado do Tratamento , Procedimentos Cirúrgicos Urológicos Masculinos/métodos
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